Bovine Aorta Endothelial Cells (BAECs)

Product Description

Bovine Aorta Endothelial Cells (BAECs) line the vessel wall of aorta, and are constantly exposed to high hemodynamic forces. They produce endothelium-derived substances regulating vasoconstriction and vessel growth ^[1]. BAECs also modulate the expression of cellular adhesion molecules to control and fine-tune inflammatory responses and fibrinolysis ^[2]. These physiological properties allow BAEC cultures to be widely used in the study of mechanisms for endothelium dysfunction, pathogenesis of vascular diseases and atherosclerosis, and the development of novel disease treatments.

iXCells Biotechnologies provides high quality BAEC, which are isolated from bovine aorta and cryopreserved at P2, with >0.5 million cells in each vial. These BAEC are negative for mycoplasma, bacteria, yeast, and fungi and can further expand for 16 population doublings in Endothelial Cell Growth Medium (Cat# MD-0010) under the condition suggested by iXCells Biotechnologies.

Product Details

References

1. Ando J, and Kamiya A. Flow-dependent regulation of gene expression in vascular endothelial cells. Heart J. 1996; 37:19-32.
2. Liu JW, Wei DZ, etc. Enhancement of fibrinolytic activity of bovine aortic endothelial cells by ginsenoside Rb2. Acta Pharmacol sin 2003; 24: 102-108.

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