Rat Sertoli Cells (RSC)

Product Description

Sertoli cells are a highly specialized cells found in the testes. They played an important role in the development and maturation of sperm cells, or spermatozoa, within the testes, a process called spermatogenesis. Because Sertoli cells function largely to assist the developing sperm cells through their maturation process, they sometimes are referred to as a nurse cell of the testicles. They are part of a seminiferous tubule and helps in the process of spermatogenesis ^[1]. Sertoli cells provide inmature models for a high potential of nursing purpos and supporting function for the maturity. 

 iXCells Biotechnologies provides high quality Rat Sertoli Cells (RSC), which are isolated from the testes of male rats aged 19-21 days (Figure 1) and cryopreserved at P0, with >1 million cells in each vial. RSC express vimentin (Figure 2) and they are negative for mycoplasma, bacteria, yeast, and fungi. RSCs can be maintained in Sertoli Cell Growth Medium (Cat# MD-0091) under the condition suggested by iXCells Biotechnologies. 

Figure 1. Rat Sertoli Cells (Phase contrast).

Figure 2. Rat Sertoli Cells are positive for Vimentin.

Product Details

References

[1]   Rato, Luís; Alves, Marco G.; Socorro, Sílvia; Duarte, Ana I.; Cavaco, José E.; Oliveira, Pedro F. (1 May 2012). "Metabolic regulation is important for spermatogenesis". Nature Reviews Urology. 9 (6): 330–338. doi:10.1038/nrurol.2012.77. PMID 22549313..

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