爱默生物科技有限公司
厦门市翔安区民安街道莲亭路811号401
(+86) 0592-7080189
support@amogene.com
Product Description
iXCells Biotechnologies provides high quality Human Umbilical Vein Endothelial Cells (HUVEC), which are isolated from human umbilical vein of mix donors, and cryopreserved at P2, with >0.5 million cells in each vial. HUVEC have “cobblestone” morphology and positive staining with vWF/Factor VIII and CD31. HUVEC are one of the mostly used cell types to study endothelial function in vitro, including angiogenesis [1], signaling pathway under normal and pathological condition such as oxidative stress, hypoxia [2] and inflammation etc. These HUVEC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi and can further expand in Endothelial Cell Growth Medium (Cat# MD-0010) under the condition suggested by iXCells Biotechnologies.
Figure 1. (A) vWF staining in HUVEC. (B) CD31 staining in HUVEC.
Product Details
Tissue |
Human umbilical cord tissue |
Package Size |
0.5x106 cells/vial |
Passage Number |
P2 |
Shipped |
Cryopreserved |
Storage |
Liquid nitrogen |
Growth Properties |
Adherent |
Media |
References
[1] Park HJ, Zhang Y, Georgescu SP, Johnson KL, Kong D, Galper JB (2006). "Human umbilical vein endothelial cells and human dermal microvascular endothelial cells offer new insights into the relationship between lipid metabolism and angiogenesis". Stem Cell Rev 2 (2): 93–102.
[2] Nallamshetty S, Chan SY, and Loscalzo J. Hypoxia: a master regulator of microRNA biogenesis and activity. Free Radic Biol Med. 2013; 64: 20-30.
[1] Park HJ, Zhang Y, Georgescu SP, Johnson KL, Kong D, Galper JB (2006). "Human umbilical vein endothelial cells and human dermal microvascular endothelial cells offer new insights into the relationship between lipid metabolism and angiogenesis". Stem Cell Rev 2 (2): 93–102.
[2] Nallamshetty S, Chan SY, and Loscalzo J. Hypoxia: a master regulator of microRNA biogenesis and activity. Free Radic Biol Med. 2013; 64: 20-30.
Biological | |
---|---|
Cell System | Vascular Cell System |
Cell Type | Endothelial Cells |
Species | Human (Normal) |