Human Cortical GABAergic Neurons (iPSC-derived, Normal)

产品代码: 40HU-010
Call for Price: 0592-7821662

产品规格

选择产品规格:
Cryopreserved, 1.0 million cells/vial
Cryopreserved, 4.0 million cells/vial

Product Description

Excitation and inhibition are the two basic interactions between neurons, which utilize glutamate and γ-aminobutyric acid (GABA) as the major neurotransmitters for excitatory and inhibitory signals, respectively. Abnormal GABAergic neuron function has been associated with multiple neurodevelopmental and neurodegenerative disorders.

iXCells™ Cortical GABAergic Neurons show high neuronal purity (>90% Tuj1 positive cells) and express typical marker GABA (Figure 1 and Figure 2) after culturing in the Cortical Neuron Maintenance Medium (Cat# MD-0093) for 5 days.

iXCells also provide customized differentiation service with your own iPS cell lines.  Please contact us at orders@amogene.com for more details.


iPSC GABAergic neurons Phase contrast

Figure 1.  Phase contrast image of iPSC-GABAergic neurons cultured in the Cortical Neuron Maintenance Medium (Cat# MD-0093) for 5 days. 

 

iPSC GABAergic neurons IF1

Figure 2.  The cryopreserved GABAergic neurons were recovered and seeded on Matrigel-coated 96-well plate and cultured in the Cortical Neuron Maintenance Medium (Cat# MD-0093) for 5 days. The cells were fixed and stained with anti-GABA (red) and anti-TUJ1 (green) antibodies.

 

Product Details

  Tissue Origin

  Human iPSC-derived GABAergic Neurons

  Package Size

  1.0 million cells/vial (cryopreserved)

  4.0 million cells/vial (cryopreserved)

  Shipped

  Frozen on dry ice

  Media

Cortical Neuron Maintenance Medium (Cat# MD-0093)

 

 Download Datasheet

[1] Yang N, Chanda S et al. (2017). “Generation of pure GABAergic neurons by transcription factor programming”. Nat Methods. 14(6):621-628.

Biological
Species Human (Normal)